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2 edition of Lactobacilli in term and preterm birth found in the catalog.

Lactobacilli in term and preterm birth

Catherine A. Jones

Lactobacilli in term and preterm birth

adherence to vaginal epithelial cells and inhibition of the growth of anaerobes in vitro

by Catherine A. Jones

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  • 21 Currently reading

Published .
Written in English


Edition Notes

Thesis (M.Sc.) - University of Surrey, 1996.

StatementCatherine A. Jones.
ContributionsUniversity of Surrey. School of Biological Sciences.
ID Numbers
Open LibraryOL19355861M

Logistic regression was used to model associations of community state type IV, a community characterized by a paucity of Lactobacillus species and a wide array of anaerobic bacteria, and short cervix (preterm birth.   Exactly why or how the presence of these species, and the relative lack of Lactobacillus, are linked to the higher rate of preterm birth isn’t clear yet. But the findings confirm other studies.

The diversity state type (CST IV), characterized by a depletion of lactobacilli and increase in anaerobic and microaerophilic bacteria, has been associated with adverse reproductive and obstetric health outcomes, including increased risk of acquiring sexually transmitted infections, pelvic inflammatory disease, endometritis, preterm birth, and.   Preterm birth is defined as delivery before 37 completed weeks of gestational age [] and can be further sub-categorized in extremely preterm (≤ 27 +6 weeks +days), very preterm (28 to 31 +6) and late preterm (32 to 36 +6) [].Preterm birth comprises 11% of all livebirths worldwide, and its complications are estimated to cause 35% of world’s neonatal deaths, which represents million.

Reference Number: Year: Authors: Fettweis J.M. et al Link: Link to original paper Health: Gut Microbiome Summary. The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in the frequency of preterm birth among populations within countries, and women of African ancestry disproportionately bear the burden of risk in the United States. Objective: To estimate the association between bidet toilet use and preterm birth, as well as the effect of bidet toilet use on bacterial vaginosis, in pregnant women. Methods: Questionnaires about bidet toilet usage were sent to 2, women who gave birth between and in Tokyo. Crude and multivariable adjusted odds ratios (ORs) for the incidence of preterm birth (delivery at less.


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Lactobacilli in term and preterm birth by Catherine A. Jones Download PDF EPUB FB2

Group 2: Treatment group. Group 2 was comprised of patients who underwent prenatal check-up at our hospital from July to April Because the Cochrane review stated that treating BV with antibiotics up to GW 20 prevents preterm delivery 6, we changed our routine practice from that adopted in Group principle, we performed BV screening tests during the EGP, and as a Cited by: 6.

In a prospective study of the presence of vaginal lactobacilli and preterm birth in 1, women with singleton pregnancies, 95% of 1, women who delivered at Ͼ37 weeks of gestation, 90% of The dependent factors were the risk of the following adverse outcomes: BV, preterm birth, chorioamnionitis, and a combined preterm birth or chorioamnionitis.

The predictors that were considered were presence or absence of vaginal lactobacilli, the maximum H 2 O 2 production level of any of the lactobacillus isolates from an individual woman Cited by:   Introduction.

The etiology of preterm birth (PTB) is multifactorial: 50% of the cases are idiopathic while 20–40% are disease specific or medically indicated deliveries such as pre-eclampsia or fetal growth restriction (FGR), which require delivery (1, 2).The remaining 25–30% of PTB can be attributed to intrauterine infection and/or inflammation (1, 2).Cited by:   The diversity of Lactobacillus species in term vs.

preterm was the main outcome measure. iners alone was detected in 11 from 13 (85%) women who delivered by: Vaginal lactobacilli play an important role in maintaining female reproductive health.

• Dysbiosis in vaginal milieu causes infections and reproductive complications. • Role and effectiveness of probiotics therapy against BV and preterm birth have been reviewed.

The microbiota of women who experienced preterm birth (term. The two groups did not cluster according to CST, likely because CST assignment is driven in most cases by the dominance of one particular species.

Several species of lactobacilli support an immunological defense system in the genital tract, along with antibacterial substances, cytokines, and defensins that help protect against dysbiosis and infections that affect pregnancy and risk of preterm birth.

7 Lactobacillus species are the most abundant strains in the vaginal tract, with. Overall, 44% of women delivered at term and 92% women delivered preterm had only one Lactobacillus spp. detectable by PCR denaturing gradient gel electrophoresis (DGGE) and sequencing in their vaginal specimens.

Around 56% women who delivered at term, and 8% who delivered preterm had a combination of 2, or more Lactobacillus spp. This statisticaly significant. Conclusion. Community state type IV, characterized by a diverse set of strict and facultative anaerobes and a paucity of Lactobacillus species, is associated with increased odds of short cervix.

Women with both community state type IV and short cervix have higher odds of spontaneous preterm birth than women with either factor alone. Introduction. Preterm birth (PTB) is a major cause of neonatal mortality worldwide [, ].Infants born preterm are more likely to suffer from respiratory distress syndrome, necrotizing enterocolitis, and intraventricular hemorrhage and developmental delays [2,4,5].Twenty-five to thirty percent of preterm births are attributed to intrauterine infection and subsequent immune response.

Babies born preterm (before completing 37 weeks in the womb) are at increased risk of long-term disability and death. The investigators do not fully understand the cause(s) of preterm birth but it occurs more frequently when the normal, healthy bacteria (called Lactobacilli) in a woman's birth canal are replaced with unhealthy bacteria.

Lactobacillus vaccines are used in the therapy and prophylaxis of non-specific bacterial vaginitis and trichomoniasis. The vaccines consist of specific inactivated strains of Lactobacilli, called "aberrant" strains in the relevant literature dating from the s.

These strains were isolated from the vaginal secretion of patients suffering from acute colpitis. Preterm birth (PTB; birth of an infant prior to 37 weeks of gestation) is a global medical concern that affects 13 million mothers and infants, annually. PTB is a syndrome with multiple etiologies.

The lactobacillus dominated environment is very stable and has been associated with a lower risk of preterm birth in comparison to lactobacilli depleted women. Women with Preterm Premature Rupture of the Membranes (PPROM) have been shown to have an absence of lactobacilli at the time of rupture, and this can persist until delivery [5] but they.

The incidence of preterm birth exceeds 10% worldwide. There are significant disparities in the frequency of preterm birth among populations within countries, and women of African ancestry. Mercer, B. Preterm premature rupture of the membranes: current approaches to evaluation and management.

Obstet. Gynecol. Clin. North Am. 32, – (   Objectives: To investigate the role of vaginal infection in preterm delivery, we studied characteristics of vaginal discharge related to hydrogen peroxide-producing s: Vaginal specimens were obtained from 66 women with normal pregnancy and 30 women with preterm labor with intact membranes.

pH, leukocyte counts on wet smear, and scores by Nugent criteria on. In this study, we use metataxonomics to longitudinally characterize the vaginal bacterial composition from as early as 6 weeks of gestation in women at high (n = 38) and low (n = 22) risk of preterm birth who subsequently experience PPROM and in women delivering at term without complications (n = 36).

Globally, preterm birth is the leading cause of death in children under 5 years with 15 million babies being born before 37 weeks’ gestation each year neous preterm birth is a.

Participants. The study population consisted of 24 (12 low birth weight and 12 normal birth weight) full-term neonates (gestational age 37 w0d–41 w6d) consecutively born at Peking Union Medical College Hospital Birth weight was used to identify cases and controls: low birth weight (LBW) is birth weight (NBW) is ≥ g and.

Figure enesis of infection/inflammation-associated preterm labor and birth. Colonization of the female genital tract by pathogenic anaerobic bacteria due to an altered vaginal microbiota triggers a feed forward inflammatory response that ultimately stimulates the pathways to preterm labor and delivery, i.e., uterine contraction, cervical remodeling and membrane activation.The absence of lactobacilli in the vagina, a specific feature of BV, raises the question as to whether restoration of lactobacilli, by probiotic therapy, can restore the normal flora and improve the chances of having a healthy term pregnancy.

The rationale for probiotic use in pregnant women is quite strong.